Post-chemotherapy serum anti-Müllerian hormone level predicts ovarian function recovery
نویسندگان
چکیده
منابع مشابه
Pretreatment anti-Müllerian hormone predicts for loss of ovarian function after chemotherapy for early breast cancer☆
AIM Improving survival for women with early breast cancer (eBC) requires greater attention to the consequences of treatment, including risk to ovarian function. We have assessed whether biochemical markers of the ovarian reserve might improve prediction of chemotherapy related amenorrhoea. METHODS Women (n=59, mean age 42.6 years [(range 23.3-52.5]) with eBC were recruited before any treatmen...
متن کاملRegulation of ovarian function: the role of anti-Müllerian hormone.
Anti-Müllerian hormone (AMH), also known as Müllerian inhibiting substance, is a member of the transforming growth factor beta superfamily of growth and differentiation factors. In contrast to other members of the family, which exert a broad range of functions in multiple tissues, the principal function of AMH is to induce regression of the Müllerian ducts during male sex differentiation. Howev...
متن کاملA highly-sensitive anti-Müllerian hormone assay improves analysis of ovarian function following chemotherapy for early breast cancer☆
AIM Anti-Müllerian hormone (AMH) shows promise as a biomarker of the ovarian reserve but current assays are insufficiently sensitive to allow assessment of this post-chemotherapy in most women. We have assessed a new highly sensitive AMH assay (Ansh picoAMH) in the evaluation of ovarian activity in women with very low ovarian reserve after chemotherapy. METHODS A prospective cohort and an ind...
متن کاملLive Birth Rate following Intrauterine Insemination in Women with Low or Very Low Level of Serum Anti-müllerian Hormone
Background: While anti-Müllerian hormone (AMH) level allows quantitative evaluation of ovarian reserve, its predictive value for live births following assisted reproductive technology cycles has remained controversial. The aim of the present study was to assess the importance of AMH in predicting live birth following intrauterine insemination (IUI) in the case of low or very lo...
متن کاملSerum anti-Müllerian hormone as a predictive marker of polycystic ovarian syndrome
BACKGROUND The anti-Müllerian hormone (AMH) is a dimeric protein secreted by the female ovaries and has two fundamental roles in follicle genesis. It delays the entrance of the primordial follicle into the pool of follicles in growth and diminishes the sensitivity of the ovarian follicle towards follicle-stimulating hormone (FSH). The purpose of this work was to study the AMH (nv 2.0-6.8 ng/mL)...
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ژورنال
عنوان ژورنال: Endocrine Connections
سال: 2018
ISSN: 2049-3614
DOI: 10.1530/ec-18-0180